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The Advantages of the Discseel® Procedure over Stem Cell Injections

Back pain is one of the most common causes of discomfort for adults, and it becomes increasingly prevalent with age. This pain can occur for many reasons, ranging from degenerative disc disease to injuries from compression or other movements. There are a number of treatment options available for these injuries, and there are a few options that can be used that do not require surgery.

Two of the most popular non-surgical treatments to treat spinal injuries are spinal stem cell injections and the Discseel® Procedure.

What are Stem Cells? 

These cells are specialized cells that are critical components in the healing process. They are able to change into a variety of different types of cells based on where they are in the body, creating new bone cells, muscle cells, cartilage cells, fibrous tissue cells, and others.

These cells can be found primarily in the bone marrow inside many bones throughout the body, and they can be extracted, or aspirated, using a needle that is directly inserted into the bone. After a sample of the bone marrow has been extracted, it is then centrifuged, allowing the various components to be isolated from one another.

At this point, the stem cell layer can be removed. Sometimes, these cells are replicated to produce an even greater number of cells before they are injected into damaged tissues in the human body. 

What are Spinal Stem Cell Injections?

These injections place stem cells directly into the affected area. Many times, this stem cell treatment is used to address damage caused by degenerative disc disease. This disease can cause the intervertebral discs between each of the vertebra in the back to dry out and crack. When this happens, the discs lose some of their function and are not able to resist compression forces as well.

In some cases, the discs can break down to the point that the gel-like fluid inside the discs can leak out. This leaking fluid can decrease the height of the damaged disc, leading to increased pain with various movements. The fluid and compressed disc can also place pressure on the nerves surrounding the spinal column. Pinched nerves can cause pain and numbness or tingling in the arms and legs.

disc explaining how an annular tears affects backpain

The idea behind this treatment is that injecting the cells into the damaged discs will allow them to differentiate into cartilage and connective tissue, helping to regenerate the discs and restore their original function. However, this treatment is not as simple as it sounds.

Potential Downfalls of Stem Cell Injections

Dr. Meyer from the Columbia Interventional Pain Center conducted a study on the effectiveness of these injections for spinal disc injuries. After performing this procedure on 24 individuals, he noted that half of them had another spinal procedure within only two and a half years. Then, out of the 12 other patients, three of them reported no pain relief after 12 months. Overall, this shows a success rate of only around 37 percent.

This low success rate illustrates the potential ineffectiveness that this treatment can have. In addition, half of the study participants undergoing further procedures to try to address their pain is a cause for concern.

Even though some pain relief has been seen with a percentage of stem cell therapy cases, the need for subsequent injections after the initial treatment is quite common. Receiving multiple injections can be financially costly and frustrating, especially if the treatments do not provide the expected benefits.

In addition to the frequent ineffectiveness, stem cell injections are also not well regulated when it comes to the sample’s preparation, quality, and concentration. These cells are all processed from the same individual they will be used in. If a person’s immune system is weaker or they do not have healthy cells, inserting these differentiating cells into the spine can have limited benefits or potentially be harmful.

The preparation process can also differ depending on the specific physician performing the aspiration and injection. Differing methods can affect the stem cell concentration of a sample and its effectiveness when used in regenerative medicine. 

A further area that is not thoroughly controlled is the accuracy of the placement of an injection. If the injection is placed in the wrong location, it can cause severe side effects. One of the largest of these is unwanted growth in certain areas.

One study noted that the cells have the possibility of spreading outside of the annulus, the outer layer, of the spinal disc. This caused abnormal growth on the outside of the vertebrae, which can lead to side effects similar to those seen with degenerative disc disease in the first place.

The Discseel® Procedure: The Better Alternative

This procedure utilizes a fibrin biologic. This biologic is approved by the FDA, ensuring that a consistent product is offered and that the results from the procedure. 

The biologic portion of the injection contains stem cells and a number of other growth factors that help to generate new tissues and restore function to damaged tissues. This portion is similar to that of the simple stem cell injection.

Fibrin is a somewhat glue-like substance, and it is naturally produced within the body after an injury occurs. It helps to close wounds and seal off damaged tissues from the outside environment so that they can heal without becoming infected. This concept is utilized with this procedure.

When the fibrin is injected into a torn or cracked disc that is leaking fluid, the fibrin can help to plug up any of the holes on the outer section of the disc. This helps to retain the remaining internal fluid. Sealing the discs traps the biologic stem cell mixture inside the disc as well, allowing it to rebuild broken down tissues in the targeted area without having the opportunity to leak out and cause abnormal growths. The ability of the fibrin to seal off the discs also prevents the need for multiple injections and treatments.

This treatment option carries a very high success rate, even for individuals who had previously tried a different spinal procedure but who did not experience favorable results. In fact, 70 percent of individuals who had undergone previous spinal treatments experienced relief with this fibrin biologic treatment. This success rate is almost twice as high as that of stem cell injections, showing that the Discseel® Procedure is a much more reliable and effective treatment option.

https://www.forbes.com/sites/victoriaforster/2018/03/05/i-work-with-stem-cells-heres-why-i-wont-be-injecting-them-into-myself/#28fae77073de

https://www.webmd.com/back-pain/news/20130412/stem-cells-to-relieve-low-back-pain#1

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737050/

https://drkevinpauza.com/procedures/pauza-disc-treatment.html

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Brandon Tolman, D.O. - Integrity Center for Regenerative Medicine

  • 5114 Old Hickory Blvd. Suite 201B, Nashville, Tennessee 37076
  • 615-846-9969

Wendi Lundquist, D.O. - Active Life Physical Medicine & Pain Center

Dr. Lundquist is the Medical Director and founder of Active Life Physical Medicine & Pain Center, Innovative Surgery Center, and Regena Spa. She is dual board certified in Physical Medicine and Rehabilitation along with Pain Management and a diplomat with the American Board of Pain Medicine. She completed her training at Loyola University in Chicago, Illinois in July of 2005. During her time there, she served as Chief Resident and was involved in several research projects. Prior to, she completed medical school at Midwestern University at the Arizona College of Osteopathic Medicine campus in Glendale, Arizona and internship at Doctors Hospital in Massillon, Ohio. She also has a Bachelor of Science in Biology and minor in Chemistry from the University of New Mexico in Albuquerque. She has a special interest in sports medicine, pain and spine. With 17 years experience, she has great enthusiasm towards regenerative medicine.

  • 15547 North Reems Road, Surprise, Arizona 85374
  • 623-535-9777

Maxim Moradian, M.D. - Interventional Spine Care & Orthopedic Regenerative Experts

Dr. Moradian is triple-board certified in Physical Medicine and Rehabilitation (PM&R), Sports Medicine and Pain Management. Dr. Moradian’s clinical practice is devoted to the comprehensive care of spine, joint, muscle, tendon, ligament, and peripheral nerve disorders. He is proficient in performing advanced, minimally-invasive procedures under fluoroscopic and/or ultrasound guidance in the entire spine. Dr. Moradian performs electrodiagnostic testing (EMG/NCS) for the accurate diagnosis of muscle and/or nerve disorders. He has a special interest in regenerative medicine, sports concussions, neuromuscular ultrasound, medical education, and clinical research. His true passion is to treat his patients like his family and friends.

  • 51 N. 5th Ave, Suite 301., Arcadia, California 91006
  • 626-460-1096

Haley Burke, M.D. - Mile High Sports and Rehab

Dr. Burke is board-certified in both Interventional Pain Management and Neurology and has completed an accredited Pain Fellowship with the Department of Anesthesiology at MD Anderson Cancer Center, one of the nation’s most prestigious hospitals. Dr. Burke completed her residency in Neurology at the University of Colorado, where she received the department’s ‘Excellence in Teaching’ award during her year as Chief Resident. Her Doctor of Medicine degree was completed at the University of Texas Health Science Center, where she was elected to the ‘Gold Humanism Honor Society.’

  • 2490 W. 26th Ave. Suite A-10., Denver, Colorado 80211
  • 303-331-6744

Desmond Hussey, M.D. - NASA Neuroscience and Spine Associates. P.L

Dr. Hussey earned his undergraduate degree from Dartmouth College, and proceeded to earn his Medical Degree from The University of Miami School of Medicine. He then attended Northwestern University Internal Medicine Program, followed by a Neurology Residency Program at Emory University. Dr. Hussey continued his specialty training at John Hopkins University pain clinic. A member of The Spinal Injection Society and The American Academy of Neurology and Psychiatry.

  • 130 Tamiami Trail North, Ste. 250., Naples, Florida 34102
  • 239-631-7150

Dmitry Buyanov, M.D. - IV Infusion Treatment Center

Dr. Buyanov is originally from Kiev, Ukraine. He received his training in Anesthesiology and his Interventional Pain Management Post-Doctoral at Penn State Medical Center, PA. Dr. Buyanov moved to San Antonio in 2003 at which time he was part of a multi-specialty group before he founded Premier Pain Consultants in 2004. His practice has over 5000 active patients in his practice. Dr. Buyanov treats his patients in a cost-effective manner although giving them the best care with interventional pain treatments/procedure to help each patient improve their quality of life. Dr. Buyanov strongly believes in an individualized and multidisciplinary approach to pain management, he believes in the Buddhist saying: “pain is inevitable but suffering is optional”. He works closely with the area internists, physical therapists, chiropractors, psychiatrists, neurologists, and spine surgeons to insure that each patient has the most optimal individualized treatment plan. Dr. Buyanov enjoys spending his spare time with his children.

  • 831 Coral Ridge Drive, Coral Springs, Florida 33071
  • 2102989004

Mark Reecer, M.D. - Fort Wayne Physical Medicine

Dr. Mark Reecer is board certified in Physical Medicine & Rehabilitation and Pain Management. He has over 20 years of work comp experience, and he routinely provides Independent Medical Examinations (IMEs) for the Indiana Workers’ Compensation Board. Dr. Reecer has lectured extensively and has authored multiple publications that promote his specialty and the use of treatment modalities to eliminate pain, improve function and avoid surgery.

  • 5750 Coventry Lane, Suite 101, Fort Wayne, Indiana 46804
  • 260-436-9337

Travis Foxx, M.D. - Premier Anesthesiology & Pain

  • 6500 W.143rd St., Overland Park, Kansas 66223
  • 913-626-4633

Janet Pearl, M.D. - The Boston Stem Cell Center

Dr. Janet Pearl has been in practice since 1999 and is the Medical Director of The Boston Stem Cell Center. She is also the Medical Director of  Complete Spine and Pain Care  an interventional integrated Pain Management practice, both located in Framingham, Massachusetts. Dr. Pearl is Triple Board Certified in Regenerative Medicine, Pain Medicine and Anesthesiology and has over 20 years experience in doing these procedures.

Previously, Dr. Pearl was the Co-Director of the Pain Management Center at St. Elizabeth’s Medical Center, where she was also the Director of the Pain Management Fellowship program.

After graduating from Harvard College with an A.B. in Applied Mathematics with Economics, Dr. Pearl received a M.Sc. in Health Planning and Financing at the London School of Hygiene and Tropical Medicine. She then received her M.D. from the Columbia College of Physicians and Surgeons, where she represented the Medical School as a senator in the Columbia University Senate.

Watch Dr Pearl give an introduction to The Boston Stem Cell Center

Dr. Pearl completed her internship in Internal Medicine at New England Deaconess Hospital, her residency in Anesthesiology at the Massachusetts General Hospital, and her fellowship in Pain Management at the Brigham and Women’s Hospital. Dr. Pearl was the first resident ever to serve on the Accreditation Council for Graduate Medical Education (ACGME)’s Residency Review Committee for Anesthesiology. She is a Joseph Collins Scholar and a Rotary Scholar and was awarded the AMA/Glaxo Welcome and AMA/Burroughs Welcome Resident Leadership Awards.

From 2004 to 2010, Dr. Pearl served on the University of Massachusetts Board of Trustees. While there she chaired the Committee on Science, Technology and Research, was a member of the Committee on Academic and Student Affairs and the Governance Committee and also served as Vice Chair of the Advancement Committee, and as a member of the Committee on Athletics.

Dr. Pearl is Board Certified in Regenerative Medicine, Pain Medicine and Anesthesiology with the American Board of Regenerative Medicine and the American Board of Anesthesiologists.

  • 600 Worcester Rd, Ste 301, Boston, Massachusetts 01702
  • 508-231-2700

Memberships:

  • The American Pain Society;
  • The Massachusetts Medical Society;
  • The Massachusetts Society of Anesthesiologists;
  • The Massachusetts Society of Interventional Pain Physicians;
  • The American Society of Anesthesiologists;
  • The American Society of International Pain Physicians;
  • The American Institute of Ultrasound in Medicine; and,
  • The American Board of Regenerative Medicine.

PUBLIC SERVICE:

  • Member, Massachusetts Department of Industrial Accidents, Health Care Services Board 
  • Member of the Association of Harvard College Class Secretaries and Treasurers
  • Past Member of the Board of Directors of the Harvard Alumni Association
  • Former Member of the Board of Trustees University of Massachusetts. (10/2010 – 10/2014) 

Kevin Pauza, M.D. - Regenerative Sportscare Institute

  • 62 E 88th Street, New York, New York 10128
  • 646-870-7997

SPECIALTY

  • Disc Biologics
  • Interventional Spine

EDUCATION & DEGREES

  • Fellowship: Interventional Spine, University of Pennsylvania
  • Residency: PM&R, University of Pennsylvania
  • Internship: Surgery & Medicine, Columbia University College of Physicians and Surgeons
  • Medical Doctorate: Pennsylvania State University College of Medicine
  • Bachelor of Arts: Biology, Lehigh University
  • Bachelor of Arts: Psychology, Lehigh University

CERTIFICATIONS & LICENSES

  • Texas State Medical and Surgical License
  • New York State Medical and Surgical License
  • Florida State Medical and Surgical License

HONORS

  • Lehigh University Four-year Academic Scholarship
  • Magna Cum Laude, Lehigh University
  • Lehigh University President’s Award
  • Lehigh University Tower Society
  • Distinguished Alumnus, Penn State University (selected from 500,000 Penn State alumni)
  • North American Spine Society, Outstanding Paper of the Year, 2003
  • President-Elect, International Spine Intervention Society
  • Founding Partner, Texas Spine and Joint Hospital
  • Commencement Speaker: Penn State University College of Medicine
  • Advisory Board, AMA
    Keynote Speaker, Harvard Pain Center Commencement
  • Founding Chairman, Standards Committee, International Spine Intervention Society
  • Chairman, Spine Committee, Amercian Academy of Physical Medicine & Rehabilitation
  • Appointed Spine Advisor, Japanese Prime Minister
  • Appointed Spine Advisor, Allied Royal Families

EXPERIENCE

  • Founding Partner & Principal, Texas Spine & Joint Hospital

Gregory Lutz, M.D. - Regenerative Sportscare Institute

Dr. Gregory Lutz is the Founder and Medical Director of the Regenerative SportsCare Institute (RSI). In addition, he currently serves as Physiatrist-In-Chief Emeritus at Hospital for Special Surgery (HSS) and a Professor of Clinical Rehabilitation Medicine at Weill Medical College of Cornell University. Dr. Lutz is one of the world’s leading experts in the field of regenerative interventional orthopedic medicine, appearing annually on Castle Connolly’s and New York Magazine’s “Top Doctors” lists.

  • 62 E 88th Street, New York, New York 10128
  • 6468707997

Thierry Bonnabesse, M.D. - Champlain Spine and Pain Management

  • 294 Tom Miller Rd, Plattsburgh, New York 12901
  • 518-324-7246 Ext 127

Boris Terebuh, M.D. - Regenerative Spine & Joint Center

Boris Terebuh, MD specializes in providing personalized nonsurgical solutions for spine problems that interfere with the function patients desire and the independence they deserve. Dr. Terebuh completed his Physical Medicine & Rehabilitation residency training at The Ohio State University in 1997 and has been in solo practice in Ohio since 2001 because he is committed to providing accessible, individualized and attentive care to his patients. His regenerative approach to solving spine problems enhances the body’s natural ability to heal itself. His guiding principle is integrity – doing what is right for patients in a conscientious manner with the motivation of helping them become fully functional, independent and satisfied. Dr. Terebuh is a very unique Medical Doctor because he has earned seven Board Certifications in the field of musculoskeletal medicine and nonsurgical spine care. Boris Terebuh, MD is delighted to be a Discseel® provider because this revolutionary new technology aligns perfectly with his preferred regenerative treatment approach and patient care philosophy. Dr. Terebuh is also grateful to Discseel® developer, Kevin Pauza, MD, for all the years of diligent and meticulous research to create this innovative, paradigm-shifting intervention, which will certainly spare countless individuals the prospect of avoidable spine surgical procedures.

  • 6860 Perimeter Drive, Suite A., Dublin, Ohio 43016
  • 614-689-0466

Kevin Pauza, M.D. - Texas Spine and Joint Hospital

Prior to attending Penn State University, Dr. Pauza earned his undergraduate degree from Lehigh University, and furthered his training with a Surgical and Medical Internship at Columbia University College of Physicians and Surgeons. He continued his specialty training at the University of Pennsylvania, followed by an Interventional Spine Fellowship. In addition to his research, philanthropic, and clinical endeavors, Dr. Pauza remains a motivated educator. He established a Spine Fellowship program and continues training physicians from around the world. He heads international committees responsible for establishing standards and educating surgical and non-surgical physicians.

  • 801 Turtle Creek Dr., Tyler, Texas 75701
  • 903-593-2222

SPECIALTY

  • Disc Biologics
  • Interventional Spine

EDUCATION & DEGREES

  • Fellowship: Interventional Spine, University of Pennsylvania
  • Residency: PM&R, University of Pennsylvania
  • Internship: Surgery & Medicine, Columbia University College of Physicians and Surgeons
  • Medical Doctorate: Pennsylvania State University College of Medicine
  • Bachelor of Arts: Biology, Lehigh University
  • Bachelor of Arts: Psychology, Lehigh University

CERTIFICATIONS & LICENSES

  • Texas State Medical and Surgical License
  • New York State Medical and Surgical License
  • Florida State Medical and Surgical License

HONORS

  • Lehigh University Four-year Academic Scholarship
  • Magna Cum Laude, Lehigh University
  • Lehigh University President’s Award
  • Lehigh University Tower Society
  • Distinguished Alumnus, Penn State University (selected from 500,000 Penn State alumni)
  • North American Spine Society, Outstanding Paper of the Year, 2003
  • President-Elect, International Spine Intervention Society
  • Founding Partner, Texas Spine and Joint Hospital
  • Commencement Speaker: Penn State University College of Medicine
  • Advisory Board, AMA
    Keynote Speaker, Harvard Pain Center Commencement
  • Founding Chairman, Standards Committee, International Spine Intervention Society
  • Chairman, Spine Committee, Amercian Academy of Physical Medicine & Rehabilitation
  • Appointed Spine Advisor, Japanese Prime Minister
  • Appointed Spine Advisor, Allied Royal Families

EXPERIENCE

  • Founding Partner & Principal, Texas Spine & Joint Hospital

Yasuyuki Nonaka, M.D. - ILC International Lumbago Clinic

  • 1-1-35 Nishiawaji, Higashiyodogawa-ku, Ōsaka-shi, Ōsaka-fu 533-0031
  • +81-6-6210-1905

Michael Wolff, M.D. - Southwest Spine & Sports

  • 9913 N 95th St., Scottsdale, Arizona 85258
  • 480-766-8255